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Will the new universal influenza vaccine BPL-1357 test successfully on humans?

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<body><h2>Influenza A</h2>
<p><a class="wiki-img" href="/mediadb/image/ddbd16048b4a46dfb87c8c67c3e15b29/"><img alt="Emergency hospital during influenza epidemic, Camp Funston, Kansas. - Copyright: Otis Historical Archives, National Museum of Health and Medicine." height="235" src="/media/displays/ddbd16048b4a46dfb87c8c67c3e15b29/wiki_medium.png" style="float:right" width="315"/></a>Of the four major strains of the influenza virus, A and B cause most human illness and the annual flu epidemics, novel A subtypes can even result in pandemics (e.g. H1N1 for the 1918 flu pandemic) and are responsible for most severe cases and deaths. [1]</p>
<h2>The novel vaccine</h2>
<p>A new universal vaccine against the influenza A virus was tested successfully on mice and ferrets.  It conferred protection against multiple distinct influenza A strains in mice and ferrets. [2] </p>
<h2>Phase 1 clinical trial</h2>
<p>A Phase 1 clinical trial of a candidate vaccine, BPL-1357 has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland. The placebo-controlled trial will test the safety and its ability to prompt immune responses. [3] It is scheduled to complete on 1 March 2023, and will generate evidence for safety and Immunogenicity against various strains. [4]</p>
<h2>Sources</h2>
<ol>
<li><strong><a href="https://www.cdc.gov/flu/about/viruses/types.htm" target="_blank">Types of Influenza Viruses</a>.</strong> CDC</li>
<li><strong><a href="https://www.science.org/doi/10.1126/scitranslmed.abo2167" target="_blank">An inactivated multivalent influenza A virus vaccine</a>. </strong><em>Science, 13 July 2022</em></li>
<li><a href="https://www.nih.gov/news-events/news-releases/trial-potential-universal-flu-vaccine-opens-nih-clinical-center" target="_blank"><strong>Trial of potential universal flu vaccine opens</strong></a><strong>.</strong> <em>NIH, 28 June 2022</em></li>
<li><strong><a href="https://www.clinicaltrials.gov/ct2/show/NCT05027932?term=NCT05027932&draw=2&rank=1" target="_blank">Safety and Immunogenicity of BPL-1357</a>.</strong> ClinicalTrials.gov, 7 July 2022</li>
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